University of Wisconsin–Madison

Year: 2025

Investigating Potential Disparities in Clinical Trial Eligibility and Enrollment at an NCI-designated Comprehensive Cancer Center

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Cancer Medicine (2023) Authors: Monica Patel, Jennifer Shah, Floyd John Brinley IV, Paul Abrahamse, Christine Veenstra, Anne Schott Abstract: Although barriers to trial accrual are well-reported, few studies have explored trial eligibility and trial offers as potential drivers of disparities in cancer clinical trial enrollment. We identified patients with gastrointestinal (GI) or head/neck (HN) malignancies who were seen as new patients …

Are Those All My Options? Evaluating Oncologists’ Communication Strategies in Treatment and Clinical Trial Discussions by Race and Gender

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Supportive Care in Cancer (2025) Authors: Monica Arun Patel, Samantha Vuong, Bonyan Qudah, Noelle K LoConte, Narjust Florez, Jennifer M Weiss, Earlise Ward, Fauzia Hollnagel, Michael C Matthews, Toby C Campbell Abstract: Increasing patient enrollment and promoting equity in trial participation are essential to improving cancer care outcomes. Physicians play a crucial role in decision-making, making it important to understand communication strategies used by oncologists when …

Associations Between Serum Vitamin D Biomarkers and Tumor Expression of Ki67, p53, and COX-2 in Colorectal Cancer Cases from the Southern Community Cohort Study

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The Journal of Steroid Biochemistry and Molecular Biology (2023) Authors: Thomas Lawler, Timothy Su, Qiuyin Cai, Mark D Steinwandel, Wei Zheng, William J Blot, Shaneda Warren Andersen Abstract: Higher 25-hydroxyvitamin D is associated with lower colorectal cancer (CRC) risk, with limited data from African Americans (AAs), who have greater risk for CRC and 25-hydroxyvitamin D deficiency. In a predominantly AA sample of …

Genome-Wide Association Study (GWAS) of Circulating Vitamin D Outcomes Among Individuals of African Ancestry

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The American Journal of Clinical Nutrition (2023) Authors: Lisa A. Parlato, Rene Welch, Irene M. Ong, Jirong Long, Qiuyin Cai, Mark D. Steinwandel, William J. Blot, Wei Zheng, Shaneda Warren Anderson Abstract: Vitamin D deficiency is more common among African-ancestry individuals and may be associated with adverse health outcomes. Vitamin D binding protein (VDBP) regulates concentrations …

Associations Between Folate and Alcohol Consumption with Colorectal Tumor Ki67 Expression in the Southern Community Cohort Study

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Nutrition and Cancer (2023) Authors: Thomas Lawler, Timothy Su, Qiuyin Cai, Mark D. Steinwandel, Wei Zheng, Shaneda Warren Andersen Abstract: Folate is hypothesized to accelerate cell proliferation in colorectal cancer (CRC) by supporting DNA synthesis, while alcohol is also linked to gastrointestinal epithelial proliferation, despite biological antagonism of folate. We report associations between folate and alcohol consumption …

Prediagnostic 25-Hydroxyvitamin D in Association with Cancer-specific and All-cause Mortality Among Low-income, Non-Hispanic Black Americans with Colorectal Cancer

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Cancer Epidemiology, Biomarkers & Prevention (2023) Authors: Thomas P Lawler, Nikhil K Khankari, Xiao-Ou Shu, Mark Steinwandel, Qiuyin Cai, Peter W Jurutka, Wei Zheng, Shaneda Warren Andersen Abstract: Observational studies show high prediagnosis 25-hydroxyvitamin D is associated with lower mortality after colorectal cancer diagnosis. Results from clinical trials suggest vitamin D supplementation may improve outcomes among patients with colorectal cancer. Most studies …

Reduced Racial Disparity in Receipt of Optimal Locoregional Treatment for Women with Early-Stage Breast Cancer

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PLOS One (2023). Authors: Hasan Nadeem, John A. Romley, Shaneda Warren Andersen Abstract: Racial disparities in breast cancer treatment contribute to Black women having the worst breast cancer survival rates in the U.S. We investigated whether differences in receipt of optimal locoregional treatment (OLT), defined as receipt of mastectomy, breast-conserving surgery, or no surgery when contraindicated, …

Race- and Gender-Specific Associations Between Neighborhood-Level Socioeconomic Status and Body Mass Index: Evidence from the Southern Community Cohort Study

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International Journal of Environmental Research and Public Health (2023) Authors: Lauren Giurini, Loren Lipworth, Harvey J. Murff, Wei Zheng, Shaneda Warren Andersen Abstract: Obesity and a low socioeconomic status (SES), measured at the neighborhood level, are more common among Americans of Black race and with a low individual-level SES. We examined the association between the …

Racial Disparities in Colorectal Cancer Clinicopathological and Molecular Tumor Characteristics: A Systematic Review

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Cancer Causes & Control (2024) Authors: Thomas Lawler, Lisa Parlato, Shaneda Warren Andersen Abstract: African Americans have the highest colorectal cancer (CRC) mortality of all racial groups in the USA, which may relate to differences in healthcare access or advanced stage at diagnosis. Recent evidence indicates that differences in tumor characteristics may also underlie disparities …

Feasibility of Precision Smoking Treatment in a Low-Income Community Setting: Results of a Pilot Randomized Controlled Trial in The Southern Community Cohort Study

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Addiction Science & Clinical Practice (2024) Authors: Scott S. Lee, Nicole Senft Everson, Maureen Sanderson, Rebecca Selove, William J. Blot, Stephen King, Karen Gilliam, Suman Kundu, Mark Steinwandel, Sarah J. Sternlieb, Qiuyin Cai, Shaneda Warren Andersen, Debra L. Friedman, Erin Connors Kelly, Mary Kay Fadden, Matthew S. Freiberg, Quinn S. Wells, Juan Canedo, Rachel F. Tyndale, Robert P. Young, Raewyn J. Hopkins, Hilary A. Tindle Abstract: The feasibility of precision smoking treatment in socioeconomically disadvantaged …