Category: Affiliate Publication

Genome-Wide Association Study (GWAS) of Circulating Vitamin D Outcomes Among Individuals of African Ancestry

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The American Journal of Clinical Nutrition (2023) Authors: Lisa A. Parlato, Rene Welch, Irene M. Ong, Jirong Long, Qiuyin Cai, Mark D. Steinwandel, William J. Blot, Wei Zheng, Shaneda Warren Anderson Abstract: Vitamin D deficiency is more common among African-ancestry individuals and may be associated with adverse health outcomes. Vitamin D binding protein (VDBP) regulates concentrations …

Associations Between Folate and Alcohol Consumption with Colorectal Tumor Ki67 Expression in the Southern Community Cohort Study

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Nutrition and Cancer (2023) Authors: Thomas Lawler, Timothy Su, Qiuyin Cai, Mark D. Steinwandel, Wei Zheng, Shaneda Warren Andersen Abstract: Folate is hypothesized to accelerate cell proliferation in colorectal cancer (CRC) by supporting DNA synthesis, while alcohol is also linked to gastrointestinal epithelial proliferation, despite biological antagonism of folate. We report associations between folate and alcohol consumption …

Prediagnostic 25-Hydroxyvitamin D in Association with Cancer-specific and All-cause Mortality Among Low-income, Non-Hispanic Black Americans with Colorectal Cancer

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Cancer Epidemiology, Biomarkers & Prevention (2023) Authors: Thomas P Lawler, Nikhil K Khankari, Xiao-Ou Shu, Mark Steinwandel, Qiuyin Cai, Peter W Jurutka, Wei Zheng, Shaneda Warren Andersen Abstract: Observational studies show high prediagnosis 25-hydroxyvitamin D is associated with lower mortality after colorectal cancer diagnosis. Results from clinical trials suggest vitamin D supplementation may improve outcomes among patients with colorectal cancer. Most studies …

Reduced Racial Disparity in Receipt of Optimal Locoregional Treatment for Women with Early-Stage Breast Cancer

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PLOS One (2023). Authors: Hasan Nadeem, John A. Romley, Shaneda Warren Andersen Abstract: Racial disparities in breast cancer treatment contribute to Black women having the worst breast cancer survival rates in the U.S. We investigated whether differences in receipt of optimal locoregional treatment (OLT), defined as receipt of mastectomy, breast-conserving surgery, or no surgery when contraindicated, …

Race- and Gender-Specific Associations Between Neighborhood-Level Socioeconomic Status and Body Mass Index: Evidence from the Southern Community Cohort Study

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International Journal of Environmental Research and Public Health (2023) Authors: Lauren Giurini, Loren Lipworth, Harvey J. Murff, Wei Zheng, Shaneda Warren Andersen Abstract: Obesity and a low socioeconomic status (SES), measured at the neighborhood level, are more common among Americans of Black race and with a low individual-level SES. We examined the association between the …

Racial Disparities in Colorectal Cancer Clinicopathological and Molecular Tumor Characteristics: A Systematic Review

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Cancer Causes & Control (2024) Authors: Thomas Lawler, Lisa Parlato, Shaneda Warren Andersen Abstract: African Americans have the highest colorectal cancer (CRC) mortality of all racial groups in the USA, which may relate to differences in healthcare access or advanced stage at diagnosis. Recent evidence indicates that differences in tumor characteristics may also underlie disparities …

Feasibility of Precision Smoking Treatment in a Low-Income Community Setting: Results of a Pilot Randomized Controlled Trial in The Southern Community Cohort Study

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Addiction Science & Clinical Practice (2024) Authors: Scott S. Lee, Nicole Senft Everson, Maureen Sanderson, Rebecca Selove, William J. Blot, Stephen King, Karen Gilliam, Suman Kundu, Mark Steinwandel, Sarah J. Sternlieb, Qiuyin Cai, Shaneda Warren Andersen, Debra L. Friedman, Erin Connors Kelly, Mary Kay Fadden, Matthew S. Freiberg, Quinn S. Wells, Juan Canedo, Rachel F. Tyndale, Robert P. Young, Raewyn J. Hopkins, Hilary A. Tindle Abstract: The feasibility of precision smoking treatment in socioeconomically disadvantaged …

Metformin’s Role in Lowering Colorectal Cancer Risk Among Individuals with Diabetes from the Southern Community Cohort Study

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Cancer Epidemiology (2024) Authors: Thomas Lawler, Zoe L. Walts, Lauren Giurini, Mark Steinwandel, Loren Lipworth, Harvey J. Murff, Wei Zheng, Shaneda Warren Andersen Abstract: Metformin, utilized to manage hyperglycemia, has been linked to a reduced risk of colorectal cancer (CRC) among individuals with diabetes. However, evidence is lacking for non-Hispanic Black individuals and those with …

Associations of Diabetes and Mortality Among Colorectal Cancer Patients from the Southern Community Cohort Study

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British Journal of Cancer (2024) Authors: Thomas Lawler, Elizabeth Hibler, Zoe L. Walts, Lauren Giurini, Mark Steinwandel, Loren Lipworth, Harvey J. Murff, Wei Zheng, Shaneda Warren Andersen Abstract: We investigated associations between diabetes and mortality among participants with incident colorectal cancer (CRC) from the Southern Community Cohort Study. Participants (73% non-Hispanic Black; 60% income < $15,000) …

Associations of Albumin and BMI with Colorectal Cancer Risk in the Southern Community Cohort Study: A Prospective Cohort Study

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Journal of Racial and Ethnic Health Disparities (2024) Authors: Zoe Walts, Lisa Parlato, Ronni Brent, Qiuyin Cai, Mark Steinwandel, Wei Zheng, Shaneda Warren Andersen Abstract: Obesity may increase colorectal cancer (CRC) risk through mechanisms of increased inflammation. Although BMI is the most used adiposity indicator, it may less accurately measure adiposity in Black populations. Herein, we investigate associations between BMI, low albumin …